A multilingual European patch test software concept: WinAlldat/ESSCA

2003 
drugs but also occupational allergens) (3–5). To our knowledge, there has never been described an erythema multiforme with contact dermatitis from rubber vulcanization agents. The lesions were the consequence of indirect occupational contact with rubber piping via the intermediary of a detachment gel able to absorb and concentrate rubber allergens. The clinical course of the disease was biphasic: initially, an acute eczema with poor response to topical corticosteroids and then erythema multiforme requiring systemic corticosteroids. The pathophysiological mechanism could be a systemic response due to the strength of the allergen or cytotoxicity as in erythema multiforme with herpetic infection (4, 5). We were amazed by the rapidity of this sensitization to rubber vulcanization agents. An occupational survey found other workers presentingwith a similar eruption at the same factory.
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