CHEMICAL STUDIES ON BLASTMYCIN. III

The antimycin A- blastmycin antibiotics are strong fungicides which have been separated into the components antimycin A1, A2, A3 (blastmycin) and A4. The structures of A1 and A3 were elucidated as I. Gas-liquid chromatographic studies of the antibiotic derivatives revealed additional components. Degradation products from the antibiotics were also investigated by gas-liquid chromatography to determine individual antibiotic structures. The blastmycin complex and antimycin A complex can be classified respectively into four and about nine members, which differ in alkyl side chain and acyloxy groups as listed in Fig. 3.