Activity of the lysosomal cysteine proteinases (cathepsin B, H, L) and a metalloproteinase (MMP-7-ase) in the serum of cystic fibrosis homozygous children

: Lysosomal cysteine proteinase (cathepsin B, H, L) and metalloproteinase (MMP-7-ase) activities were measured from serum of 19 cystic fibrosis (CF) homozygotes and of 13 healthy children, as control group. The activity of cathepsin B and H significantly increased in the CF-group.