POLYMERIC NANOGELS AS SYSTEMS FOR DRUG DELIVERING

Selective delivery of drugs in the body is the focus of many research groups in the world. One of the promising nanocontainers is nanogel soft nanoparticles, consisting of hydrophilic or amphiphilic polymeric chains. Nanogels have beneficial characteristics: high loading capacity, stability and sensitivity to environmental changes (pH, ionic strength and temperature). We can use nanogels with biodegradable cross-links to avoid long-term accumulation of nanocontainers in the body. The aim of this work was to synthesize nanogels and to study loading and release kinetic of anticancer drug Doxorubicin.