CONTROLLED / MODIFIED RELEASE oral formulations methylofainidatis

The invention is directed to oral modified / controlled release methylphenidate formulations which provide a rapid initial onset effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for immediate release methylphenidate formulations, and the duration of the effect is rapidly falls at the end of the dosing interval so as not to affect the patient's appetite in the main meal or bedtime then the patient.