Prevalencia y control de los factores de riesgo cardiovascular en pacientes con diabetes mellitus tipo 1 candidatos a trasplante renopancreático entre los años 1999 y 2010

espanolObjetivo: Estudiar la evolucion de la prevalencia y control de los factores de riesgo cardiovascular (FRCV) en una cohorte de pacientes con diabetes mellitus tipo 1 (DM1) e insuficiencia renal terminal (IRT) candidatos a trasplante renopancreatico a lo largo de 12 anos. Material y metodos: Se estudia a los pacientes con DM1 e IRT remitidos a nuestro centro para valoracion de trasplante renopancreatico, entre los anos 1999 y 2010. Se dividieron en 6 grupos bianuales y se analizo la evolucion del control de FRCV (control glucemico, perfil lipidico, presion arterial y tabaquismo). Se considero mal control si: hemoglobina glucosilada (HbA1c) > 7%, colesterol unido a lipoproteinas de baja densidad (cLDL) > 100 mg/dl; presion arterial (PA) ≥ 140/90 mmHg y habito tabaquico activo o pasado. Resultados: Se incluyo a un total de 270 individuos (62,9% varones), con una edad de 37,4 ± 14,9 anos y una duracion de la diabetes de 24,7 ± 12,2 anos. La HbA1c media fue de 7,8 ± 6,83 y el cLDL de 105,06 ± 25,11 mg/dl. El porcentaje de pacientes con HbA1c Conclusiones: Aunque el control de los FRCV en los pacientes con DM1 e IRT ha mejorado en los ultimos anos, este sigue siendo insuficiente. Se necesita aumentar los esfuerzos para optimizar el manejo en este grupo de poblacion. EnglishTo study the evolution of the prevalence and control of the cardiovascular disease risk factors (CVDRFs) in a cohort of patients with type 1 diabetes (DM1) and end-stage renal disease (ESRD) candidates for kidney-pancreas transplant. Patients with DM1 and ESRD sent to our centre for evaluation of kidney-pancreas transplant between the years 1999-2010 were studied. They were divided into six biannual groups and the trend of CVDRFs control was evaluated (glycaemic control, lipids values, blood pressure and smoking habits). Poor control was considered if: HbA1c greater than 7%, LDL greater than 100 mg/dL; blood pressure greater than 140/90 mmHg and current or ex-smokers. A total of 270 patients were included (62.9% male), with a mean age of 37.4 ± 14.9 years and a mean time since onset of diabetes of 24.7 ± 12.2 years. The mean HbA1c was 7.8 ± 6.83 and mean LDL was 105.06 ± 25.11 mg/dL. The percentage of patients with HbA1c Although the control of cardiovascular risk factors in patients with DMT1 and ESRD has improved over the last few years, it continues to be inadequate. An increased effort is required in order to optimise the management of this population group