Caracterização imunofenotípica e avaliação quantitativa do infiltrado linfocítário junto às áreas de displasia epitelial da próstata de cães adultos sexualmente intactos

Canine prostatic studies have been common due to high incidence of prostatic diseases in these animals and similarities with alterations in human prostatic gland. Due the high frequency of dysplasia associated with interstitial lymphocitary infiltrate and acinar atrophy in canine prostate, the aims in this study were the immunophenotypic characterization and the quantitative evaluation of the same infiltrated using anti-CD3 and anti-CD79a to T and B lymphocytes, respectively. Forty two epithelial dysplasic lesions were graduated in discrete (48%), moderate (38%) and accentuated (14%). Lymphocitary periacinar infiltrate in dysplasic areas was T type and interaction between dysplasia grade and marker was observed, with oscillation of T and B cells in according with epithelial dysplasia grade.