Epidemiological characteristics of 4428 hand food and mouth disease cases in Ji-ning city

Objective To understand the epidemiologic feature of hand food and mouth disease (HFMD) EV71 cases in Jining city.Methods 4428 cases were selected from Infectious Diseases Hospital of Jining city from March 2010 to August 2011.Real-time RT-PCR was used to detect the clinical specimens.Results 4428 cases of hospitalized patients were enrolled (sex ratio 1.9 ∶ 1).Most of the subjects were between 6 months and 5 years old (93.54％,4142/4428).The total positive rate of HFMD cases was 93.54％ (4142/4428).The positive rate of severe cases was 63.84％ (2827/4428),separately.Conclusions The positive rate of HFMD was higher from April to August.EV71 was the main pathogen of HFMD in Jining.The constituent ratio of 2011 was higher than 2010. Key words: Hand foot and mouth disease;  EV71 ;  Real-time RT-PCR