trans-Adenosine 3′,5′-Cyclic N,N-Dimethylphosphoramidate Ether Solvate, a Cyclic Nucleotide with an Equatorial Dimethylamino Group on Phosphorus.

Abstract trans-Adenosine 3′ 5′ -cyclic N,N-dimethylphosphoramidate ether solvate crystallizes as monoclinic prisms elongated about the b-axis. The dioxaphosphorinane ring adopts a flattened chair conformation with an almost planar dimethylamino substituent equatorial. The purine ring conformation is anti. The ribose ring exists in a 3T4 conformation.