Correlation of the local distribution of topically applied substances inside the stratum corneum determined by tape-stripping to differences in bioavailability.

H.-J. Weigmann,Juergen Lademann,S. Schanzer,U. Lindemann,R. von Pelchrzim,H. Schaefer,Wolfram Sterry,Vinod P. Shah

Correlation of the local distribution of topically applied substances inside the stratum corneum determined by tape-stripping to differences in bioavailability.

2001

H.-J. Weigmann
Juergen Lademann
S. Schanzer
U. Lindemann
R. von Pelchrzim
H. Schaefer
Wolfram Sterry
Vinod P. Shah

Tape-stripping and optical spectroscopy are used as a suitable combined method to determine the horny layer profile. Firstly, typical ultraviolet filter substances are used as active substances which

Keywords:

Dermatology
Absorption (pharmacology)
Horny layer
Stripping (chemistry)
Dosage form
Bioavailability
Chromatography
Stratum corneum
Chemistry
combined method

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