Making bioceramics from CaBiPO-apatite

To make ceramic antibacterial biocompatible material, we synthesized mixed calcium–bismuth oxophosphate (CaBiPO-apatite) with apatite structure. A mixture of CaBiPO-apatite and ammonium carbonate was used to prepare ceramic material in tablet form. Qualitative and quantitative phase analyses using powder XRD combined with IR spectroscopy shown the absence of any phase or chemical changes in the material during the process of making ceramics. In vitro experiment with human mesenchymal stromal cells showed high biocompatibility of the material caused by structural type and high porosity of material, despite the presence of bismuth in composition of the substance.