The Relevance of High Pulse Pressure and Renal Function in Patients with Chronic Kidney Disease: Analysis for each Stage of Chronic Kidney Disease

Background: In our previous study, we showed that high pulse pressure (PP) is associated with decreased renal function in chronic kidney disease (CKD) patients. In recent years, there were a few reports that CKD stage classification focused on glomerular filtration rate, which is associated with the occurrence of cardiovascular disease, deterioration of renal prognosis, and life prognosis. We aim to examine the relationship between increased PP and renal function according to each CKD stage classification. Methods: The present study includes 104 participants with CKD (stage G3a-G5) who visited the Nephrology Medicine Department of Yokosuka Kyousai Hospital between September 2006 and October 2011. The participants were categorized on the basis of PP: ≥65 mmHg was the High PP group, and