Investigation on medication compliance and its influencing factors in patients with stable COPD

Objective To evaluate the medication compliance and its influencing factors in patients with stable chronic obstructive pulmonary disease (COPD).Methods The intervening measures were taken in 100 patients with stable COPD,with a regular follow-up.A questionnaire method was used to investigate the medication compliance of patients in this study.The difference of medication compliance was compared between before and after intervention,and the influencing factors were analyzed.Results There were 34％ patients with good medication compliance before intervention,and 73％ after intervention,the difference was statistically significant (x2 =30.57,P ＜ 0.01).These factors which included inhalation technique mastery of medication,living alone,periodic review,and adverse drug reactions affected apparently medication compliance of patient,and these difference were statistically significant (x2 =22.99,15.52,17.94,10.04,respectively;P ＜ 0.01)between "yes" and "no" about above factors; also the medication adherence were different in patients with different age or educational level,and the difference was statistically significant (x2 =4.58,4.92,respectively; P ＜ 0.05).Conclusions The different intervening measures should be used in patients with stable COPD according to different patients' characteristics,which can enhance their medication compliance,reduce the frequency of exacerbations and improve their quality of life. Key words: Pulmonary disease, chronic obstructive;  Medication therapy;  Stable stage; Compliance ;  Influencing factors