CALCIFYING EPITHELIAL ODONTOGENIC TUMOR: A CASE REPORT

Calcifying epithelial odontogenic tumor (CEOT) is a rare, benign odontogenic neoplasm with aggressive biologic behavior. A 29-year-old woman presented at the university hospital with a complaint of a painless swelling in the right mandibular region that was fibrous in consistency on palpation. Computed tomography (CT) revealed a well-defined radiolucency (3.5 × 2.8 × 2.0 cm) in the mandibular body, permeated by foci of calcification, associated with the crown of an unerupted molar. Cortical expansion and focal areas of perforation were identified. Based on CT, the differential diagnosis included: calcifying cystic odontogenic tumor, calcifying epithelial odontogenic tumor, ameloblastic fibro-odontoma and adenomatoid odontogenic tumor. The microscopic examination revealed sheets of polyhedral, neoplastic, odontogenic epithelial cells with prominent cellular outlines and intercellular bridges. Calcified areas and eosinophilic amyloidlike material were identified. The diagnosis of CEOT was given. Mandibular segmental resection and reconstruction with titanium plate was performed with no recurrence after 3 years’ follow-up.