Analysis of cognitive function in refractory frontal epilepsy
2016
Objective
To investigate the effect of abnormal electrical activity and seizure on cognitive function in patients with refractory frontal lobe epilepsy.
Methods
From August 2010 to August 2013, the clinical data of 42 patients with frontal lobe epilepsy (Engel classification grade Ⅰ) treated surgically at the Epilepsy Center, Yuquan Hospital, Tsinghua University were analyzed retrospectively. The reasoning ability, language ability, attention function, and executive function of the patients were analyzed, and the influence of the above factors on different cognitive function was investigated in accordance with abnormal electrical activity discharge index, sides, and seizure characteristics.
Results
The Wisconsin Card Sorting Test of 42 patients was affected by the sides of abnormal electrical activity, the scores of the left side, bilateral sides, and multifocal abnormal electrical activities were decreased significantly (all P 50%) or the secondary tonic-clonic seizures occurred frequently (>1 time/day), the semantic processing scores were decreased (all P 50%) and secondary tonic-clonic seizures were decreased (all P<0.05).
Conclusion
Discharge index, sides of abnormal electrical activity, seizure frequency, and seizure types during waking and sleeping periods affects cognitive function in different degrees.
Key words:
Epilepsy, frontal lobe; Cognition disorders; Electroencephalography; Discharge index
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
0
References
0
Citations
NaN
KQI