Rhodium(III)‐Catalyzed Alkylation of Primary C(sp3)—H Bonds with α‐Diazocarbonyl Compounds.

Rh(III)-catalyzed intermolecular chelation-assisted insertion of carbenes derived from α-diazocarbonyl compounds into non-acidic primary sp3 C–H bonds, for the first time, is reported under mild reaction conditions, thus affording a good complement to previous metal-carbenoid-induced primary C(sp3)–H insertion reactions. We believe that this method will open up a new avenue for primary sp3 C–H functionalization with α-diazocarbonyl compounds.