Antimicrobial Relevance of Cu(II) Complexes of Thiophene-2-glyoxal-p-halogen Substituted Anils

Isomeric complexes of, p-chloro, p- bromo, and p-iodo - anils of 2-thiophene glyoxal ligands have been synthesized and characterized by metal analysis, molecular weight, infrared and UV- Visible spectroscopy, molar conductance and magnetic measurements. All non electrolytic complexes are square planar paramagnetics. Among all of the compounds only p-bromo and p-iodo-anils of 2-thiophene glyoxal exhibited good antifungal activity against both test fungi but all products showed moderate to good bactericidal effect against S.aures and X.holicicola bacteria.