HUMAN EPIDIDYMIS PROTEIN 4 IS A NOVEL FIBROSIS MARKER TO PREDICT PATHOLOGICAL CARDIAC REMODELING AND ADVERSE OUTCOMES IN PATIENTS WITH DILATED CARDIOMYOPATHY

The prognosis of dilated cardiomyopathy (DCM) remains unfavorable because of progressive depression of cardiac function. Cardiac interstitial fibrosis plays a crucial role in the pathophysiology of DCM. Human Epididymis Protein 4 (HE-4), novel fibrosis marker, is specifically expressed in activated