Activated M2 macrophage contributes to the pathogenesis of IgG4‐related disease via TLR 7/ IL ‐33 signaling

Noriko Ishiguro,Masafumi Moriyama,Katsuhiro Furusho,Sachiko Furukawa,Takuma Shibata,Yusuke Murakami,Akira Chinju,A. S.M.Rafiul Haque,Yuka Gion,Miho Ohta,Takashi Maehara,Akihiko Tanaka,Masaki Yamauchi,Mizuki Sakamoto,Keita Mochizuki,Yuko Ono,Jun-Nosuke Hayashida,Yasuharu Sato,Tamotsu Kiyoshima,Hidetaka Yamamoto,Kensuke Miyake,Seiji Nakamura

Activated M2 macrophage contributes to the pathogenesis of IgG4‐related disease via TLR 7/ IL ‐33 signaling

2019

Objective IgG4‐related disease (IgG4‐RD) is a unique inflammatory disorder in which Th2 cytokines promote IgG4 production. In addition, recent studies have implicated the Toll‐like receptor (TLR) pathway. This study was undertaken to examine the expression of TLRs in salivary glands (SGs) from patients with IgG4‐RD.

Keywords:

IgG4-related disease
Immunology
Medicine
Diabetes mellitus
Interleukin 33
M2 Macrophage
CD163
Pathogenesis
Agonist
Immune system
Toll-like receptor
Cytokine
Receptor

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations