TİMOMA VE CERRAHİ SONUÇLARIMIZ

OBJECTIVE: This study aims to retrospectively evaluate the survival criteria of 39 patients operated on for thymoma concerning age, sex, symptoms, smoking history, operation type, presence of MG, thymic pathology, length of hospital stay, the diameter of the mass, stage, RT and/or KT, and complications according to WHO classification and Masaoka staging. MATERIAL AND METHODS: In this study, 50 patients who were operated on for thymoma in Ataturk Chest Diseases and Thoracic Surgery Education and Research Hospital between 2000 and 2010 were examined. 11 patients were excluded from the study because 3 patients refused postoperative treatment; 3 patients discontinued treatment, and the information about 5 patients was not available. As a result, 39 patients (25 males, 14 females) were included in the study. Complete resection was performed in 35 cases, and incomplete resection was performed in 2 cases. Besides, surgical diagnostic procedures were performed in 2 cases. Medial sternotomy was performed in 30 cases (76.9%), right thoracotomy in 6 cases (15.4%) and left thoracotomy in 3 cases (7.7%). RESULTS: The patients’ ages ranged from 23 to 88 years. The mean age of the patients was 51.3 ± 15.3 (years). 25 (64.1%) of them were male and 14 (35.9%) of them were female. Postoperative complications occurred in 6 patients (15.4%) (1 patient had hoarseness due to recurrent nerve injury; 4 patients had atelectasis, and 1 patient had pneumothorax on the 6th postoperative day). One patient died due to intraoperative myocardial infarction. In our WHO histopathological classification cases, 8 (20.5%) type A, 5 (12.8%) type AB, 4 (10.3%) type B1, 1 (2.6%) type B1 / B2, 9 (23.1%) type B2, 4 (10.3%) type B2 / B3, 5 (12.8%) B3, 3 (7.7%) C were determined respectively. 9 (23.1%) type B2 and 8 (20%, 5) type A were the most common groups. Masaoka clinical stage was 11 (28.2%) stage 1, 10 (25.6%) stage 2A, 8 (20.5%) stage 2B, 8 (20.5%) stage 3, 2 (5.1%) stage 4. The 3-year, 5-year and 8-year survival rates were as follows; 96.5%, 75.1%and 67.6% of the patients. The mean life expectancy was 102.8months. Crude mortality rate was 20.5% (8/39). In our study,according to Masaoka staging, type 1 and 2A were the mostcommon while type B2 and type A were the most common according to WHO classification. The 3, 5 and 8-year survival rates of the patients were found as follows; 96.5%, 75% and 67.6% CONCLUSIONS: The best results in thymoma are obtained through total surgical resection. There was no positive effect of incomplete resection on survival. Prognosis is related to stage, histology and whether the surgical resection is complete. Prognosis is very promising in early-stage tumors.