A quantum mechanical Interaction of human erythrocytes

Theory predicts that the membrane potential will polarize membrane molecules and cause them to vibrate coherently at a frequency of ~ 1011 Hz. If the supply of metabolic energy exceeds a minimum value, membrane phonons may condense their momentum into a single "giant" vibrational mode. At 1011 Hz ionic screening is small up to distances of approximately a micrometre, so forces of a range several orders of magnitude longer than chemical forces can arise. These forces may be attractive or repulsive depending on frequency. They should occur in every metabolically active membrane and may control macromolecular transport and enzyme–substrate interactions. We find that normal human erythrocytes in plasma form rouleaux faster than Brownian motion predicts. When cells are fixed in glutaraldehyde or are metabolically depleted, or if the membrane potential is brought to zero, the rate of aggregation agrees with Brownian theory. When the metabolically depleted cells are revived or if the membrane potential is restor...