TMEM70 facilitates biogenesis of mammalian ATP synthase by promoting subunit c incorporation into the rotor structure of the enzyme

Jana Kovalčíková,Marek Vrbacký,Petr Pecina,Kateřina Tauchmannová,Hana Nůsková,Vilma Kaplanová,Andrea Brazdova,Lukáš Alán,Jan Eliáš,Kristýna Čunátová,Vladimir Korinek,Radislav Sedlacek,Tomáš Mráček,Josef Houštěk

TMEM70 facilitates biogenesis of mammalian ATP synthase by promoting subunit c incorporation into the rotor structure of the enzyme

2019

Jana Kovalčíková
Marek Vrbacký
Petr Pecina
Kateřina Tauchmannová
Hana Nůsková
Vilma Kaplanová
Andrea Brazdova
Lukáš Alán
Jan Eliáš
Kristýna Čunátová
Vladimir Korinek
Radislav Sedlacek
Tomáš Mráček
Josef Houštěk

Biogenesis of F1Fo ATP synthase, the key enzyme of mitochondrial energy provision, depends on transmembrane protein 70 (TMEM70), localized in the inner mitochondrial membrane of higher eukaryotes. ...

Keywords:

ATP synthase
Inner mitochondrial membrane
Enzyme
Cell biology
Transmembrane protein
Endocrinology
Internal medicine
Biology
Protein subunit
Biogenesis
Mitochondrion

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