Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV

Nikki Mulligan,Brookie M. Best,Jiajia Wang,Edmund V. Capparelli,Alice Stek,Emily Barr,Shelley Buschur,Edward P. Acosta,Elizabeth Smith,Nahida Chakhtoura,Sandra K. Burchett,Mark Mirochnick

Dolutegravir pharmacokinetics in pregnant and postpartum women living with HIV

2018

Nikki Mulligan
Brookie M. Best
Jiajia Wang
Edmund V. Capparelli
Alice Stek
Emily Barr
Shelley Buschur
Edward P. Acosta
Elizabeth Smith
Nahida Chakhtoura
Sandra K. Burchett
Mark Mirochnick

Objective:To evaluate dolutegravir pharmacokinetics during pregnancy compared with postpartum and in infant washout samples after delivery.Design:Ongoing, nonrandomized, open-label, parallel-group, multicenter phase-IV prospective study of antiretroviral pharmacokinetics in HIV-infected pregnant wom

Keywords:

Dolutegravir
Prospective cohort study
Medicine
Immunology
Integrase inhibitor
Internal medicine
Pharmacokinetics
Pregnancy
human immunodeficiency virus
perinatal transmission
Pediatrics

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