Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype

Wilson Lek Wen Tan,Chukwuemeka George Anene-Nzelu,Eleanor Wong,Mick Lee,Hui San Tan,Sze Jing Tang,Arnaud Michel Yvon Perrin,Kan-Xing Wu,Wen Hao Zheng,Robert John Ashburn,Bangfen Pan,May Yin Lee,Matias Ilmari Autio,Michael Morley,Wai Leong Tam,Christine Cheung,Kenneth B. Margulies,Leilei Chen,Thomas P. Cappola,Marie Loh,John C. Chambers,Shyam Prabhakar,Roger Foo

Epigenomes of Human Hearts Reveal New Genetic Variants Relevant for Cardiac Disease and Phenotype

2020

Rationale: Identifying genetic markers for heterogeneous complex diseases such as heart failure is challenging, and requires prohibitively large cohort sizes in genome-wide association studies (GWA...

Keywords:

Diabetes mellitus
Cardiology
Phenotype
Bioinformatics
Genetic association
Genetic marker
Disease
Chromatin
Internal medicine
Biology
Heart failure
genetic variants

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