Abstract 17086: Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Leads To More Severe Anemia In A Murine Model Of Sickle Cell Disease

Introduction: Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a protease produced by the liver that targets the low density lipoprotein receptor (LDLR) for degradation. Deficiency of PCSK9...