Drug resistance and transposon and insertion sequence of multi-drug resistant Acinetobacter baumannii.

OBJECTIVE To explore the relationship between resistance of multidrug-resistant Acinetobacter baumannii and transposon and insertion sequence.METHODS K-B method was used to detect the resistance.PCR was used to analyze the transposon and insertion sequence.RESULTS The resistant rates of A.baumannii were cefotaxime 78.9%,ceftazidime 63.1%,cefepime 78.9%,ceftazidime 100.0%,imipenem 73.7%,meropenem 73.7%,ampicillin 78.9%,amoxicillin 78.9%,amikacin 52.6%,gentamicin 57.8%,ciprofloxacin 78.9% and tetraycline 78.9%,respectively.The detection rate of tnp513 was 47.4%,Isaba1 was 78.9% and IS 26 was 47.4%.CONCLUSION The resistance of multi-drug resistant A.baumannii is associated with transposon and insertion sequence.