Screening for Barrett's esophagus by balloon cytology.

Objective : to determine whether balloon cytology would allow a nonendoscopic diagnosis of Barrett's esophagus. Methods : In 10 unselected patients with Barrett's esophagus, balloon cytology was performed with a Brandt esophageal cytology balloon catheter prior to endoscopy/esophageal biopsy. Specimens were cytologically evaluated for the presence of goblet cells and/or dysplasia. Results : No patient had goblet cells or definitive columnar cell dysplasia. Conclusion : This technique with a commercially available balloon catheter does not allow for a nonendoscopic diagnosis of Barrett's esophagus.