The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice

Misa Hirose,Paul Schilf,Sarah Rohde,Yask Gupta,Tiphaine Sancerni,Marie-Clotilde Alves-Guerra,Christian Sina,Robert Jaster,Bruno Miroux,Saleh M. Ibrahim

The mitochondrial uncoupling protein 2 gene is causal for the spontaneous polycystic liver diseases in mice

2017

Misa Hirose
Paul Schilf
Sarah Rohde
Yask Gupta
Tiphaine Sancerni
Marie-Clotilde Alves-Guerra
Christian Sina
Robert Jaster
Bruno Miroux
Saleh M. Ibrahim

• Mice deficient in the mitochondrial uncoupling protein 2 gene ( Ucp2 −/− ) spontaneously developed polycystic liver diseases (PCLDs) at the age of 12 months.

Keywords:

Genetics
Molecular biology
Biology
Uncoupling protein 2
Endocrinology
Gene
Internal medicine
PRKCSH
blood chemistry
LRP5
Dominance (genetics)
SEC63
Biomarker (medicine)
Mitochondrion

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