TRRD and COMPEL Databases on Transcription Linked to TRANSFAC as Tools for Analysis and Recognition of Regulatory Sequences

Two new databases have been developed to provide the comprehensive research on mechanisms controlling eukaryotic gene expression on the transcription level: TRRD (Transcription Regulatory Region Database) for accumulation of data about structural and functional organisation of gene regulatory regions, and COMPEL - the database on composite regulatory elements that contains contiguous or overlapping binding sites for different transcription factors. Link between TRRD, COMPEL and TRANSFAC through the common table “GENES” has been established. Computer analysis of the transcription regulatory sequences collected in the databases have been carried out by means of SITEVIDEO system. SITEVIDEO offers the following programs: search for significant oligonucleotides in a 15-letter code; dinucleotide weight consensus; analysis of DNA conformation parameters.