The applicator can be integrated into the built-in non-verbal guidance equipment

The subject of the invention relates to an applicator may be incorporated into a built-in non-verbal guidance apparatus compact, the applicator device having a micro-perforated skin painlessly and optionally having an active agent, the active agent storage a first chamber in said applicator for applying a positive area of ​​skin to be perforated. The micro-device of the applicator may include a micro-needle, microneedle array, microblades, micro blade array, a micro-tool, the tool array of micro Functional microarrays (FMAs). The method of compliance of the predetermined non-verbal compact built-in calibration device using the guidance of the applicator, e.g., to indicate that the light force is applied to the micro device for the perforation of the recommended amount of skin to the skin. The applicator is adapted to provide enhanced delivery of active agents for the therapeutic or cosmetic treatment, and active agent (e.g., L-carnitine, insulin, botulinum toxin, etc.) of local or systemic delivery improved.