Pneumopericardium and pneumomediastinum caused by inhalation of laughing gas from a gas cartridge

Laughing gas inhalation is frequently used for intoxication purposes. This case report describes a 25-year-old man, who suffered from both pneumopericardium and pneumomediastinum after having inhalated laughing gas. After three days of observation, he was discharged from hospital without any complications. Pneumopericardium and pneumomediastinum are very rare but potentially life-threatening complications of laughing gas inhalation.