Correspondence re: A. E. Biemer-Huttmann et al., Mucin Core Protein Expression in Colorectal Cancers with High Levels of Microsatellite Instability Indicates a Novel Pathway of Morphogenesis. Clin. Cancer Res., 6: 1909 -1916, 2000.

In a recent study, Biemer-Huttmann et al. [(1)][1] reported that the expression of both MUC2 and MUC5AC mucins is significantly associated with sporadic colorectal carcinomas with MSI-H.[1][2] Because the coexpression of both MUC2 and MUC5AC was observed in 68% of a series of 22 MSI-H cancers and