Mikrozirkulationsstörungen bei Diabetes mellitus Typ 2

Microcirculation impairments in patients suffering from diabetes mellitus type 2 are the end point of a pathological cascade. Diabetic long-term damages are actually early damages, because they already begin, when diabetes type 2 is not yet diagnosed, but there ”only” exists a pronounced dysfunction of the beta cells in the patient. In the center of the linked metabolic pathways, which result in a microcirculation impairment, are the advanced glycation endproducts = AGEs, the reactive oxygen species = ROS, inflammatory mediators and nitrogen monoxide NO. The therapeutic action has to be orientated according to the key factors. In nutritional counselling, patients should be informed about the development of AGE’s by baking and frying and as well as about AGE’s in soft drinks. In patients with diabetes mellitus type 2, the defense mechanisms against reactive oxygen species, which are developed by the body, are not sufficient. An administration of antioxidants seems to make sense. Nutrition should by rich in secondary components of plants. The different inflammatory mediators cause a systemic inflammation, therefore an anti-inflammatory therapy makes sense. The anti-inflammatory complex homeopathic agent Traumeel is presented. In patients with diabetes mellitus type 2 and microcirculation impairments often there is not enough NO present, which is vasodilatively effective, therefore an oral supplementation of L-arginin as a precursor of NO can be recommended. The phytotherapeutic agent Ginkgo biloba and the homeopathic agent Vertigoheel improve the microcirculation additionally.