Graphene and Graphene-related Materials as Brain Electrode

The neural electrodes were used for acquiring neuron signals in brain-machine interfaces, and it is crucial for next-generation neuron engineering and related medical application. Thus, developing flexible, stable and high-resolution neural electrodes will play an important role in stimulation, acquisition, recording and analysis of signals. Compared with traditional metallic electrodes, graphene and other two-dimensional materials have attracted wide attention in electrophysiological recording and stimulation due to their excellent physical properties such as unique flexibility, low resistance, and high optical transparency. In this review, we reviewed the recent progress on graphene, graphene/polymers compound and graphene-related materials electrodes for neuron signals recording, stimulation, and related coupling technology with optical signal, which provides an outlook on the nanotechnology-neuron interface as well as a medical diagnosis of electrodes.