Identification of potent agonists of photoreceptor-specific nuclear receptor (NR2E3) and preparation of a radioligand.
2006
Agonists of NR2E3 (PNR, RNR) have been identified and optimized to EC 50 < 200 nM. A tritiated analogue of one agonist was prepared to aid in the development of a binding assay.
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