Novel agonist of α 4 β 2 * neuronal nicotinic receptor with antinociceptive efficacy in rodent models of acute and chronic pain
2018
Objective
To demonstrate the antinociceptive and antihypersensitivity mechanisms of Cris-104 (1-{2-[5-(4-fluorophenyl)–1H-pyrazol-4-yl]ethyl}piperidine), a novel selective α4β2* nicotinic acetylcholine receptor (nAChR) agonist, in rodent acute/inflammatory and chronic pain models.
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