A Low Temperature Co-Fired Ceramic Mesofluidic Separator

A 3-dimensional mesofluidic separator has been successfully designed and fabricated using a low-temperature co-fired-ceramic (LTCC) technology. This mesofluidic separator consists of several vertical micro-channels and horizontal distribution cavities to create the velocity increase before entering a bent microchannel. The centrifugal force created by the bent microchannel further increases the fluid velocity to enhance the plasma skimming effect. Separation of the white and red blood cells in anti-coagulated blood has been demonstrated using this mesofluidic separator.