Validation of Test Weighing Protocol to Estimate Enteral Feeding Volumes in Preterm Infants

Objective To evaluate the accuracy of pre- and postfeeding weights to estimate enteral feeding volumes in preterm infants. Study design Single-center prospective cohort study of infants 28-36 weeks' corrected age receiving gavage feedings. For each test weight, 3 pre- and 3 postgavage feeding weights were obtained by study personnel, blinded to feeding volume, via a specific protocol. The correlation between test weight difference and actual volume ingested was assessed by the use of summary statistics, Spearman rho, and graphical analyses. The relationship between categorical predictive variables and a predefined acceptable difference (±5 mL) was assessed with the χ 2 or Fisher exact test. Results A total of 101 test weights were performed in 68 infants. Estimated and actual feeding volumes were highly correlated (r = 0.94, P P = .04) when concerns about protocol adherence were noted (eg, difficulty securing oxygen tubing). Conclusions Via the use of a standard protocol, feeding volumes can be estimated accurately by pre- and postfeeding weights. Test weighing could be a valuable tool to support direct breastfeeding in the neonatal intensive care unit.