The Researches and Applications of Liposomes for Delivery of Anticancer Agent

Cancer is one of the major threats to human health.Treatment with high-dose chemotherapeutic agent is one of the conventional therapies.However,most of the anticancer agents with highly cytotoxic activity are also cytotoxic to common cells in cancer therapy.Patients often suffer from the adverse reactions while undergoing chemotherapeutic treatment,thus the living quality of patients is reduced.Pharmaceuticals researchers should select and aim at the drug delivery system with high-effectiveness,enhanced-targeting and low side reaction.Liposomes,as its unique physics and chemistry properties and drug delivery mechanism,have been a hot topic in the use and research of anticancer agent delivery system.This review combining with recent foreign and domestic data,mainly focuses on the advantages of liposomal drug delivery system,research progress and formulations problems.Based on analyzing the industrialization of liposomes,we prospect the development of this new DDS in anticancer drug deliver research.