An Update on Ovarian Aging and Ovarian Reserve Tests
2015
Ovaries are the female organs that age more quickly than other tissues such as the
uterus, the pituitary gland or pancreas. Different from males, an interesting question
is why and how the females lose fertility so rapidly. During the aging process, both
the number and quality of the oocytes in the ovaries decrease and reach to a point
beyond that no more viable offspring may be produced and the associated cyclic
endocrinological activities cease, entering the menopause in females at an average
age of 50 years. Females who delayed childbearing with or without their willing
until their 30 years or 40 years constitute the largest portion of the total infertility
population. Ovarian reserve tests (ORTs) provide an indirect estimate of a female’s
diminishing ovarian reserve or remaining follicular pool. This article briefly reviews
recent progresses in relation to ovarian aging and ORTs.
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