Effect of cervical sympathetic block on burned rat kidney and its related mechanisms

Objective:To investigate the effect of cervical sympathetic block(CSB) on the kidney of burned rats. Methods:SD rats were divided into Control,Burned and CSB groups. The roles of CSB were evaluated by comparing renal function and structure,blood pressure,renal blood flow volume,expression of Bcl-2 and T-AOC in the kidney were detected. Results:The renal blood flow volume in CSB group was higher than that of burned group. The function and structure of the kindney in CSB group were better than those in Burned group. CSB could increase the T-AOC and expression of Bcl-2 in the kidney. Conclusions:CSB can improve the renal blood perfusion of severely burned rats,enhance anti-oxidant capacity and prevent renal dysfunction after burn injury.