EFFECT ON ISOFLURANE ANAESTHESIA AND SURGERY ON THYROID FUNCTION IN MAN

THE Er'rr.CTS of various anaesthetic agents on the activity of the thyroid gland have been reported. 1-5 However, no study has been published on the effects of isoflurane anaesthesia on thyroid function. The present study was undertaken to investigate the effects of isoflurane anaesthesia and surgery on serum thyroxine concentrations, in the belief that exploration of the role of thyroid activity as an endocrine response to acute stress would be helpful in the management of patients with abnormal thyroid function.