Index of the Impact and the Convalescence of the Antiparasitic Chemotherapy (Avomec 1%, Rombendazol 2.5%, Tylosinum 200 ) at Infected Cattles (S.papillosus, D.lanceolatum)

Parasitic impact on indices of the immunogram index in cattles infected with Strongyloides papillosus is 14,3%, while those infected with Dicrocoelium lanceolatum - 19,2%, due to the persistent parasite toxins that inhibit polyclonal proliferation of immunocompetent cells that are involved in cellular immune response. Index of the chemotherapy impact (Avomec 1%, Tylosinum 200) on the immunogram indices at cattles infected with stongiloidose, is 14,9%, while those of dicroceliose treatement (Rombendazol 2,5%, Tylosinum 200) represents 17,9%. These changes are due to the imunotoxic effect of parasiticide drugs and degradation products of parasitic elements after treatment. Index of the posttherapeutic convalescence, over 56 days on average, in cattles infected with S.papillosus (Avomec 1%, Tylosinum 200) is 19,4%, and after the therapy of infected animals with D.lanceolatum (Rombendazol 2,5%, Tylosinum 200) it becomes – 14,0%. Thus antiparasitic treatement aggravates the disease process, causes immunodeficiency with long reconvalescence and decreases animal resistance to reinfestation Posttherapeutic recovery period (Avomec 1% Tylosinum 200) of the immunogram indices in cattle affected by the strongiloidose is 34-40 days, and after treating (Rombendazol 2,5%, Tylosinum 200) animals sick with dicroceliose – 45-50 days.These results are due to cumulative pathogenetic factors and parasitic drugs.