Functional monitoring of lung tissue using a hybrid hyperspectral Time-Resolved GASMAS system: a systematic study on ex vivo sample.

A portable hybrid system of three optical techniques GASMAS (Gas in scattering media absorption spectroscopy), TR-NIRS (time-resolved near-infrared spectroscopy) and CWBS (continuous wave broadband spectroscopy) have been proposed to monitor optical properties and gas concentration during the gas exchange in an ex vivo bovine lung. Increasing levels of lung inflation at different pressures showed significant changes in optical properties and gas dynamics, providing valuable insights for non-invasive monitoring of lung function.