A case of leukocytoclastic vasculitis following influenza vaccination

Leukocytoclastic vasculitis (LCV) is a small-vessel vasculitis that presents with palpable purpura, most often on the lower extremities. The most common identified triggers of LCV are infection or exposure to a new medication. However, in many cases, a cause cannot be identified.1 We present a patient who had LCV during the fall season of 2 consecutive years. A cause could not be identified at the time of the initial presentation. However, upon recurrence 1 year later, it was discovered that both episodes occurred 11 days after influenza vaccination.