Mechanisms of drug resistance and detection of drug resistance gene of Mycoplasma pneumoniae

Mycoplasma pneumoniae is one of common pathogens in community-acquired pneumonia. Serious infected patients can have multiple organ injury, encephalitis and even death. Now macrolide antibiotics are choice drugs used for treatment of mycoplasma infection in children, but it is reported that drug resistance has been increasing in recent years. This article reviews macrolide resistance, mechanisms of drug resistance,and status and prospects of drug resistance gene detection of Mycoplasma pneumoniae. Key words: Mycoplasma pneumoniae; Macrolide antibiotics; Drug resistance; Gene detection