Research Progress in Circulating MicroRNAs of Body Fluid

Circulating microRNAs( miRNAs) are a family of important small non-coding RNA molecules, which participate in communication between different cells. Because circulating miRNA can be used as biomarkers of many diseases,it has attracted more attention recently. The sources and existence forms of circulating miRNAs were briefly summarized,sample preparation and detection methods of circulating miRNAs were analyzed. Additionally, the applications of circulating miRNAs were also discussed. It can provide references for further study and use of miRNAs in theory and practice fields.