Display of Self-Peptide on Adeno-Associated Virus Capsid Decreases Phagocytic Uptake in Vitro.

Tawana M. Robinson,Maria Y. Chen,Michael T. Lam,Matthew R. Ykema,Junghae Suh

Display of Self-Peptide on Adeno-Associated Virus Capsid Decreases Phagocytic Uptake in Vitro.

2020

Tawana M. Robinson
Maria Y. Chen
Michael T. Lam
Matthew R. Ykema
Junghae Suh

Adeno-associated virus (AAV) vectors are currently investigated as gene transfer agents for the treatment of a variety of diseases. However, activation of the host immune response upon vector admin...

Keywords:

Cell biology
Acquired immune system
Virus
Mutant
Chemistry
Immune system
Transduction (genetics)
In vitro
Capsid
Adeno-associated virus

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