Cardiorespiratory Performance and Acute Effect of High-intensity Exercise on Lipid Profile in Hypertensive Sedentary Older Adults with and without Diabetes Mellitus

Abstract Purpose The aim of this study was to verify if the association of hypertension and diabetes mellitus could lead to the differences on cardiorespiratory fitness and lipid profile in older adults. Methods 40 older adults were divided into two groups: Hypertensive (HTN) and Hypertensive-diabetic (HTN + T2DM). Maximum exercise test on a treadmill was conducted. Lipid profiles assessment was conducted before and after exercise. The cardiorespiratory fitness (CRF) variables were peak oxygen consumption (VO2peak), time to reach peak oxygen consumption (TVO2peak), carbon dioxide ventilatory equivalent (VE/VCO2) and carbon dioxide production (VCO2). To test intergroup and intragroup analyses independent and paired t-tests were used before and after acute exercise. Multiple linear regression was performed to test the influence of coexistence of HTN and T2DM on CRF. Results CRF measures such as VO2peak (β = -3.90), VCO2 (β = -3.87) and TVO2peak (β= -115.79) were significantly (p-value Conclusion HTN + T2DM older adults had poorer CRF. Acute changes in lipemia were similar in both groups.