Proteolytic activity in isolated perfused liver of normal and x-irradiated rats.

Uptake and catabolism of131 I-labeled denatured albumin was studied in perfused liver isolated from fed, starved, and starved x-irradiated (24 hours after 800 R) rats. Uptake of albumin and proteolytic activity is greater in starved rats than in fed rats. X-Irradiation depresses the uptake of albumin by the liver but does not affect or even increases proteolytic activity.